Bortezomib activity and in vitro interactions with anthracyclines and cytarabine in acute myeloid leukemia cells are independent of multidrug resistance mechanisms …
H Minderman, Y Zhou, KL O'Loughlin… - Cancer chemotherapy and …, 2007 - Springer
… (MDR) proteins expressed in AML cells. We also tested … bortezomib interactions with
cytarabine and anthracyclines are affected by p53, because proteasome inhibition stabilizes p53 …
cytarabine and anthracyclines are affected by p53, because proteasome inhibition stabilizes p53 …
Bortezomib activity and in vitro interactions with anthracyclines and cytarabine in acute myeloid leukemia cells are independent of multidrug resistance mechanisms …
M Hans, Y Zhou, L O'Loughlin Kieran… - Cancer Chemotherapy …, 2007 - search.proquest.com
… (MDR) proteins expressed in AML cells. We also tested … bortezomib interactions with
cytarabine and anthracyclines are affected by p53, because proteasome inhibition stabilizes p53 …
cytarabine and anthracyclines are affected by p53, because proteasome inhibition stabilizes p53 …
Activity of bortezomib in adult de novo and relapsed acute myeloid leukemia
L Gil, J Styczynski, D Dytfeld, R Debski… - Anticancer …, 2007 - ar.iiarjournals.org
… anthracyclines and cytarabine in acute myeloid leukemia cells are independent of multidrug
resistance mechanisms and p53 status. Cancer Chemother Pharmacol 60: 245-255, 2007. …
resistance mechanisms and p53 status. Cancer Chemother Pharmacol 60: 245-255, 2007. …
Phase I and pharmacokinetic study of bortezomib in combination with idarubicin and cytarabine in patients with acute myelogenous leukemia
EC Attar, DJ DeAngelo, JG Supko, F D'Amato… - Clinical cancer …, 2008 - AACR
… However, bortezomib has limited single-agent activity in … bortezomib interacts synergistically
with anthracyclines and/or … cells are independent of multidrug resistance mechanisms …
with anthracyclines and/or … cells are independent of multidrug resistance mechanisms …
In vitro activity of bortezomib in cultures of patient tumour cells—potential utility in haematological malignancies
K Wiberg, K Carlson, A Åleskog, R Larsson, P Nygren… - Medical oncology, 2009 - Springer
… pattern as well as for combination experiments, cytarabine, cisplatin, … as well as tubulin-associated
multi-drug resistance. … in vitro data indicate that bortezomib activity is independent …
multi-drug resistance. … in vitro data indicate that bortezomib activity is independent …
Proteasome inhibition in myelodysplastic syndromes and acute myelogenous leukemia cell lines
JL Liesveld, KE Rosell, J Bechelli, C Lu… - Cancer …, 2011 - Taylor & Francis
… In the HL60 line, inhibited by FTI and bortezomib independently, the combination did not …
bortezomib cytotoxicity or in vitro interactions with anthracyclines or cytarabine (Citation26). …
bortezomib cytotoxicity or in vitro interactions with anthracyclines or cytarabine (Citation26). …
Molecular mechanisms of drug resistance in acute myeloid leukaemia
DP McLornan, MF McMullin, P Johnston… - Expert opinion on drug …, 2007 - Taylor & Francis
… (often cytarabine [Ara-C] in combination with an anthracycline, such … This so-called multi-drug
resistance (MDR) is a major … , in combination with bortezomib can effectively overcome this …
resistance (MDR) is a major … , in combination with bortezomib can effectively overcome this …
Deciphering the therapeutic resistance in acute myeloid leukemia
C Gurnari, S Pagliuca, V Visconte - International journal of molecular …, 2020 - mdpi.com
… Of note, the use of proteasome inhibitors, such as bortezomib… of mutation affecting prognosis,
being related to anthracycline … Multidrug resistance (MDR) efflux transporters of the ABC (…
being related to anthracycline … Multidrug resistance (MDR) efflux transporters of the ABC (…
Effect of noncompetitive proteasome inhibition on bortezomib resistance
X Li, TE Wood, R Sprangers, G Jansen… - JNCI: Journal of the …, 2010 - academic.oup.com
… Primary human acute myeloid leukemia (AML) and chronic … of 5AHQ cell viability and
proteasome activity in K562 cells, … multidrug resistance drug efflux transporters that can confer a …
proteasome activity in K562 cells, … multidrug resistance drug efflux transporters that can confer a …
Loss of the histone methyltransferase EZH2 induces resistance to multiple drugs in acute myeloid leukemia
S Göllner, T Oellerich, S Agrawal-Singh, T Schenk… - Nature medicine, 2017 - nature.com
… Chemotherapy with cytarabine (AraC) and an anthracycline … independent drug resistance
model of doxorubicin-resistant … that bortezomib treatment could overcome drug resistance in …
model of doxorubicin-resistant … that bortezomib treatment could overcome drug resistance in …